Local anesthesia toxicity review.
نویسنده
چکیده
منابع مشابه
A review of local anesthetic cardiotoxicity and treatment with lipid emulsion
Cardiovascular collapse from accidental local anesthetic toxicity is a rare but catastrophic complication of regional anesthesia. The long-acting amide local anesthetics bupivacaine, levobupivacaine and ropivacaine have differential cardiac toxicity, but all are capable of causing death with accidental overdose. In recent times, the chance discovery that lipid emulsion may improve the chance of...
متن کاملCentral nervous system and cardiac effects from long-acting amide local anesthetic toxicity in the intact animal model.
With the development of the newer long-acting amide local anesthetics,ropivacaine and levobupivacaine, numerous animal studies of LA systemic toxicity have emerged. Because of the complex nature of the human response to LA intoxication, the task of designing and interpreting these animal studies of LA toxicity can be difficult. Accordingly, this report will review the selection of an animal mod...
متن کاملLocal anesthetic toxicity and lipid resuscitation in pregnancy.
PURPOSE OF REVIEW Lipid emulsion has emerged as an effective treatment of local anesthetic-induced cardiac arrest, but its therapeutic application for the obstetric patient requires definition at present. This review discusses clinical reports, relevant laboratory studies, and future directions for the development of an optimal protocol for lipid resuscitation in pregnancy. RECENT FINDINGS Se...
متن کاملRopivacaine induced acute neurotoxicity after epidural injection.
Ropivacaine is an amide-type long acting local anaesthetic. According to experimental and human data, its toxicity for Central Nervous System (CNS) and Cardiovascular System (CVS) is considered lower than toxicity related to bupivacaine, the now-a-days accepted golden standard for long acting local anaesthetics. Nevertheless, reports about this kind of accidents are fairly numerous. Aim of this...
متن کاملEssentials of local anesthetic pharmacology.
It is impossible to provide effective dental care without the use of local anesthetics. This drug class has an impressive history of safety and efficacy, but all local anesthetics have the potential to produce significant toxicity if used carelessly. The purpose of this review is to update the practitioner on issues regarding the basic pharmacology and clinical use of local anesthetic formulati...
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ورودعنوان ژورنال:
- Pediatric dentistry
دوره 21 6 شماره
صفحات -
تاریخ انتشار 1999